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Download e-book for iPad: Neuroscience at a Glance by Stephen Barasi, Michael J. Neal, Roger Barker

By Stephen Barasi, Michael J. Neal, Roger Barker

ISBN-10: 0865428697

ISBN-13: 9780865428690

This article covers the whole neuroscience requirement of the pre-clinical medication direction in a logical sequence of double-page spreads. It acknowledges the interdisciplinary nature of neuroscience, and the necessity to combine students' wisdom of anatomy, biochemistry, body structure and pharmacology. Examples of the physiological platforms of the valuable anxious approach and its illnesses are seen from the molecular via to the behavioural point. The textual content is logically divided into seven sections, beginning with a basic advent entitled "Cellular Neurosciences" which covers the constitution and serve as of the CNS on the microscopic point. the subsequent sections disguise cutaneous and visceral sensation, motor keep watch over and co-ordination of stream, the brainstem and designated senses. better features (memory, temper and cognition), and damage and getting old (dementias) are handled within the ultimate sections.

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Extra resources for Neuroscience at a Glance

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FEBS Lett 310(3): 273-276. Beier K, Volkl A, et al. 1997. TNF‐a downregulates the peroxisome proliferator activated receptor‐a and the mRNAs encoding peroxisomal proteins in rat liver. FEBS Lett 412 (2): 385-387. Berger J, Albet S, et al. 1999. The four murine peroxisomal ABC‐transporter genes differ in constitutive, inducible and developmental expression. Eur J Biochem 265(2): 719-727. Berger J, Molzer B, et al. 1994. X‐linked adrenoleukodystrophy (ALD): A novel mutation of the ALD gene in 6 members of a family presenting with 5 different phenotypes.

37 38 2 Adrenoleukodystrophy: Molecular, metabolic, pathologic, and therapeutic aspects Fourcade S, Savary S, et al. 2003. Thyroid hormone induction of the adrenoleukodystrophy‐related gene (ABCD2). Mol Pharmacol 63(6): 1296-1303. Gartner J, Dehmel T, et al. 2002. Functional characterization of the adrenoleukodystrophy protein (ALDP) and disease pathogenesis. Endocr Res 28(4): 741-748. Gilg AG, Singh AK, et al. 2000. Inducible nitric oxide synthase in the central nervous system of patients with X‐adrenoleukodystrophy.

1997). , 1992). , 1999). , 1995). , 2003). , MCP‐1, MCP‐3, SDF‐2). , 2003). , 2003). , 2005). , 2002), indicating that the observed higher levels of chemokines in histologically normal‐looking areas of ALD brain may be responsible for recruitment of vascular immune cells to ALD brain. , 2000). , 2004) indicate a role for decreased peroxisomes in the pathobiology of neuroinflammatory disease. , 2000) indicate overall negative consequences for myelin synthesis/repair processes. , 2003). , 2003).

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Neuroscience at a Glance by Stephen Barasi, Michael J. Neal, Roger Barker

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