By Andrew Krentz
Whereas diabetes can often be well-controlled utilizing smooth cures, metabolic emergencies unavoidably happen. This e-book presents an easy-to-read but complete account of emergencies in diabetes comfortably amassed into one quantity. for every subject, a short overview of the pathophysiology is through an outline of cardinal medical positive factors, scientific and biochemical overview and scientific administration.
- Clear, informative textual content for quick and straightforward assimilation
- Emphasis on evidence-based medicine
- Effective use of illustrations to focus on and summarize key points
Designed to slot very easily into the pocket of a white coat, this ebook could be easily at hand in all clinic clinical wards, really A&E. it will likely be worthwhile to junior medical institution medical professionals throughout quite a lot of specialties, senior condominium officials ordinarily scientific education, and nurses desirous about the care of sufferers with diabetes.
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Extra resources for Emergencies in Diabetes: Diagnosis, Management and Prevention
Use of base in the treatment of severe acidemic states. Am J Kid Dis 2001; 38: 703–727. Krentz AJ and Nattrass M. Acute metabolic complications of diabetes. In: Pickup JC, Williams G (Eds). Textbook of Diabetes, 3rd ed. Oxford. Blackwell 2003 pp. 1–24. McGarry JD and Foster DW. Regulation of hepatic fatty acid oxidation and ketone body production. Annu Rev Biochem 1980; 49: 395–420. Miles JM, Rizza RA, Haymond MW and Gerich JE. Effects of acute insulin deﬁciency on glucose and ketone body turnover in man.
Hyperosmolar non-ketotic hyperglycaemia develops gradually over hours or days. e. approximately 10 L. This water loss causes an increased plasma tonicity, which shifts water together with potassium out of cells into the extracellular space. At the same time, hydrogen ions are shifted into the cell. Consequently, despite marked renal potassium losses, plasma potassium levels are usually normal or elevated, and the blood pH is in the normal range at time of admission. Dehydration is a prominent features of hyperosmolar nonketotic hyperglycaemia.
It is more common in children with newly diagnosed type 1 diabetes. 5 Clinical features of cerebral oedema complicating diabetic ketoacidosis headache confusion irritability reduced conscious level convulsions small pupils increasing blood pressure, slowing pulse papilloedema – not always present acutely possibly impaired respiratory drive Subclinical brain swelling appears to be common during the treatment of diabetic ketoacidosis, and may be present even before intravenous rehydration is commenced.
Emergencies in Diabetes: Diagnosis, Management and Prevention by Andrew Krentz