Press "Enter" to skip to content

Dopamine and Sleep: Molecular, Functional, and Clinical by Jaime M. Monti, S. R. Pandi-Perumal, S. Chokroverty PDF

By Jaime M. Monti, S. R. Pandi-Perumal, S. Chokroverty

ISBN-10: 3319464353

ISBN-13: 9783319464350

ISBN-10: 331946437X

ISBN-13: 9783319464374

This publication deals a entire yet hugely readable compilation of papers at the position of dopamine in sleep and sleep problems. prime specialists in sleep medication, psychiatry and neuroendocrinology offer a large standpoint at the box, from confirmed theories to the newest learn advances. consequently, it represents an interdisciplinary, state of the art advisor for sleep problem experts, sleep researchers, psychiatrists, neurologists, pulmonologists, psychologists, and behavioral sleep medication specialists.

Show description

Read or Download Dopamine and Sleep: Molecular, Functional, and Clinical Aspects PDF

Similar anatomy books

Download e-book for iPad: Musculoskeletal Ultrasound: Anatomy and Technique by John M.D. O’Neill (auth.), John M.D. O’Neill MB, B.A.O,

Ultrasound is a powerful imaging modality more and more used for musculoskeletal assessment via radiologists, basic practitioners, activities medication experts, and orthopedic surgeons alike. right ultrasound exam and interpretation hinges on thorough wisdom of proper anatomy, artifacts and method.

Get Atlas of Functional Shoulder Anatomy PDF

The aim of this Atlas is to concentration the reader's realization on a chain of bone, ligament, muscle and tendon buildings and ultrastructures that experience now not up to now been mentioned other than within the most up-to-date overseas literature and in expert journals. This Atlas additionally offers tremendous high-definition photos of "targeted" sections acquired from cadavers preserved utilizing cutting-edge options.

New PDF release: Biochemistry of Smooth Muscle Contraction

This necessary source presents a scientific account of the biochemistry of gentle muscle contraction. As a finished consultant to this quickly turning out to be zone of analysis, it covers the constitution and attribute homes of contractile and regulatory proteins, with distinctive emphasis on their envisioned functionality within the stay muscle.

Download e-book for kindle: Netter’s Concise Orthopaedic Anatomy by Jon C. Thompson MD

Netter’s Concise Orthopaedic Anatomy is a best-selling, transportable, full-color source first-class to have to be had in the course of your orthopaedic rotation, residency, or as a short look-up in perform. Jon C. Thompson offers the newest facts in completely up-to-date diagnostic and therapy algorithms for all stipulations whereas conserving the preferred at-a-glance desk structure from the former variation.

Extra resources for Dopamine and Sleep: Molecular, Functional, and Clinical Aspects

Example text

In an initial study in one patient who had been in a MCS for 5 months, amantadine had a dose-dependent effect on arousal as assessed by coma-near coma scores (Zafonte et al. 1998). More recently, in a placebo-controlled trial, amantadine accelerated the pace of functional recovery in patients with post-traumatic disorders of consciousness (Giacino et al. 2012). This is currently the only pharmacological agent which has been shown to be effective in improving clinical and motor function in VS/MCS in a well controlled clinical trial.

2011) whereas drugs that enhance the extracellular concentration of catecholamines by enhancing release or blocking reuptake increase wakefulness. Similarly, wakefulness is enhanced in dopamine transporter knock-out mice (Wisor et al. 2001). The localization of catecholamine neurons was facilitated by the development of the Falck-Hillarp staining technique which allowed visualization of their location based on the chemical reaction between catecholamines and formaldehyde, leading to cyclization of the catecholamines and the formation of strongly fluorescent products (Carlsson et al.

In Drosophila, dopamine promotes arousal by inhibition via D1-like receptors in the sleep-promoting dorsal fan-shaped body as well as D1-receptor effects on the mushroom body regions involved in learning and memory. E. Brown Genetic variations in dopamine clearance affect sleepiness associated with prolonged wakefulness. Alterations in the availability of dopamine D2 receptors in the nucleus accumbens following prolonged wakefulness may be involved in this homeostatic regulation of sleepiness. Dopaminergic stimulants effectively counteract this sleepiness and ameliorate cognitive impairments associated with sleep deprivation in mammals and in Drosophila, supporting the use of wake-promoting dopaminergic agents to treat excessive daytime sleepiness in narcolepsy and Parkinson’s disease.

Download PDF sample

Dopamine and Sleep: Molecular, Functional, and Clinical Aspects by Jaime M. Monti, S. R. Pandi-Perumal, S. Chokroverty


by Kevin
4.5

Rated 4.09 of 5 – based on 35 votes