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Comparative Endocrinology by U.S. Von Euler (Eds.) PDF

By U.S. Von Euler (Eds.)

ISBN-10: 0123955491

ISBN-13: 9780123955494

ISBN-10: 0323146090

ISBN-13: 9780323146098

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Sample text

Material stainable by Gomori's method has been found in the neurohypophyseal vessels of the giraffe (Hanström, 1952), the rat (Rothballer, 1953), and the dog (Scharrer and Frandson, 1954). Heller and Lederis (1962), in electronmicrographs of the rabbit pituitary, have recently noted structures within capillaries which look like the hormone-carrying vesicles or granules, but this was seen so rarely that it may well represent an artifact. F. Storage in the Neural Lobe Neurosecretory material and hormonal activity are present in several parts of the hypothalamo-neurohypophyseal system but in those forms which possess a neural lobe, this structure must be regarded as the main site of storage, both in terms of abundance of neurosecretory material and of hormone content.

NEUROHYPOPHYSEAL HORMONES 49 that these glands contained a mixture of arginine vasopressin and oxytocin. An investigation of the chromatographically separated and partially puri­ fied hormones obtained from the neurohypophyses of collared peccaries (Pecan tajacu) and white-lipped peccaries (Tayassu pecan), presently in progress in the writer's laboratory, shows further that both arginine vaso­ pressin and lysine vasopressin may occur in the same neural lobe. Both vasopressins may also occur in a single gland of the African wart hog (Phacochoerus aethiopicus) or lysine vasopressin may be present alone.

6, 14-20. ~ 2 ~ Neurohypophyseal H. Hormones HELLER Department of Pharmacology, University of Bristol, Bristol, England I. INTRODUCTION 26 II. MAMMALIAN NEUROHYPOPHYSEAL HORMONES A. Standardization B. Chemistry C. Pharmacological Activity of the Pure Mammalian Peptides D . Structure-Action Relationships of Neurohypophyseal Hormones and Some of Their Synthetic Analogs E. Neurosecretion and the Ultrastructure of the HypothalamoNeurohypophyseal System F. Storage in the Neural Lobe G. Occurrence in the Hypothalamus H.

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Comparative Endocrinology by U.S. Von Euler (Eds.)

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