By Philip B. Mead M.D. (auth.), William J. Ledger (eds.)
The intent to organize this quantity on antibiotics for the surgeon taking care of ladies used to be dependent upon the editor's belief that the subject material had by no means been totally built for the obstetrician-gynecologist. so much textbooks of infectious illness have a small part dedicated to antibiotics, which has little relevance for the doctor taking care of post-operative or post-partum infections. easy antibiotic pharmacology is defined and there's a reflex prohibition of antibiotics for the pregnant lady. effectively, the reader assumes that the authors themselves don't deal with ladies with bacterial infections of the pelvis. fresh texts in infectious illness in obstetrics gynecology were little larger. even though the point of interest has been extra clini cally orientated, house standards have too frequently stored the discussions at a superficial point. a complete concentration upon antibiotics during this quantity gets rid of the restraints of area in earlier courses. the best gift in my activity as editor of this quantity is said to the standard of the person authors. they vary from former scholars, to con transitority colleagues, to revered friends in infectious illness. because the caliber of this quantity is expounded to the sum overall of the person chapters, I desire to remark approximately all the individuals. Philip Mead from the college of Vermont is an previous pal, who brings to the query of prophylactic antibiotics, his extensive medical event and encyclopedic knowledge.
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Additional info for Antibiotics in Obstetrics and Gynecology
May 31, 1980 22. Cron RS, Stauffer J, Paegel H, Jr: Morbidity studies in one thousand consecutive hysterectomies. Am J Obstet GynecoI63:344, 1952 23. DeSwiet, MD, Ramsey ED, Rees GM: Bacterial endocarditis after insertion of intrauterine contraceptive device. Br Med J 3:76, 1975 24. DuffP, Park RC: Antibiotic prophylaxis in vaginal hysterectomy: a review. Obstet GynecoI55:193S, 1980 25. (Editorial) Antibiotic accountability. N Engl J Med 301:380, 1979 26. Everett ED, Hirshmann JF: Transient bacteremia and endocarditis prophylaxis: A review.
May 31,1980 31. Gibbs RS, Weinstein AJ: Bacteriologic effects of prophylactic antibiotics in cesarean section. Am J Obstet GynecoI126:226, 1976 32. Gibson CD, Jr, Thompson WC, Jr: The response of burn wound staphylococci to alternating programmes of antibiotic therapy. Antibiot Annu 1955-56, p. 32 33. Glover MW, Nagell JR: The effect of prophylactic ampicillin on pelvic infection following vaginal hysterectomy. Am J Obstet GynecoI126:385, 1976 34. : Anaerobic microflora of the cervix in healthy women.
The dosage schedule should also take into account the sensitivity pattern of the infecting organism. Thus, the appropriate dosage for each patient should be the one which will produce antibiotic levels in serum and tissues sufficiently high to combat an infection caused by microorganisms with a sensitivity pattern that renders them amenable to treatment with the antibiotic in question. The pharmacokinetic studies on which dosage recommendations are based have been carried out in healthy volunteers as well as in patients with various diseases, but for obvious reasons they are never carried out in pregnant women.
Antibiotics in Obstetrics and Gynecology by Philip B. Mead M.D. (auth.), William J. Ledger (eds.)